Publications

  1. Wang X, Guo B, Li Q, Peng J, Yang Z, Wang A, Li D, Hou Z, Lv K, Kan G, Cao H, Wu H, Song J, Pan X, Sun Q, Ling S, Li Y, Zhu M, Zhang P, Peng S, Xie X, Tang T, Hong A, Bian Z, Bai Y, Lu A, Li Y, He F, Zhang G (Corresponding Author), Li Y (Corresponding Author). miR-214 targets ATF4 to inhibit bone formation. Nat Med. 2013 Jan;19(1):93-100
  2. Wang XL, Xie XH, Zhang G, Chen SH, Yao D, He K, Wang XH, Yao XS, Leng Y, Fung KP, Leung KS, Qin L. Exogenous phytoestrogenic molecule icaritin incorporated into a porous scaffold for enhancing bone defect repair. J Orthop Res. 2013 Jan;31(1):164-72
  3. Xie XH, Wang XL, Zhang G, He YX, Leng Y, Tang TT, Pan X, Qin L. Biofabrication of a PLGA-TCP-based porous bioactive bone substitute with sustained release of icaritin. J Tissue Eng Regen Med. 2012 Dec 18
  4. Baosheng Guo, Songlin Peng, Chao Liang , Xiaojuan He, Cheng Xiao, Cheng Lu, Miao Jiang, Hongyan Zhao, Aiping Lu (Corresponding Author), Ge Zhang (Corresponding Author). Recent developments in bone anabolic therapy for osteoporosis. Expert Review of Endocrinology & Metabolism 2012 Nov; 7(6): 677-685
  5. Chen SH, Wang XL, Xie XH, Zheng LZ, Yao D, Wang DP, Leng Y, Zhang G (Corresponding Author), Qin L (Corresponding Author). Comparative study of osteogenic potential of a composite scaffold incorporating either endogenous bone morphogenetic protein-2 or exogenous phytomolecule icaritin: an in vitro efficacy study. Acta Biomater. 2012 Aug;8(8):3128-37
  6. Zhu GY, Wong BC, Lu A, Bian ZX, Zhang G, Chen HB, Wong YF, Fong WF, Yang Z. Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells. Chem Pharm Bull (Tokyo). 2012;60(8):1029-36.
  7. Wei F, Moore DC, Li Y, Zhang G, Wei X, Lee JK, Wei L. Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway. Arthritis Res Ther. 2012 Jul 31;14(4):R177
  8. Xie XH, Wang XL, He YX, Liu Z, Sheng H, Zhang G (Corresponding Author), Qin L (Corresponding Author). Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis. Arthritis Rheum. 2012 May;64(5):1562-71
  9. Zhu HM (Co-first author), Qin L (Co-first author), Garnero P (Co-first author), Genant HK (Co-first author), Zhang G (Co-first author), Dai K, Yao X, Gu G, Hao Y, Li Z, Zhao Y, Li W, Yang J, Zhao X, Shi D, Fuerst T, Lu Y, Li H, Zhang X, Li C, Zhao J, Wu Q, Zhao SJ. The first multicenter and randomized clinical trial of herbal Fufang for treatment of postmenopausal osteoporosis. Osteoporos Int. 2012 Apr;23(4):1317-27.
  10. Zhang G (Corresponding Author), Guo B, Wu H, Tang T, Zhang BT, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D, Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L (Corresponding Author), Qin L (Corresponding Author). A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nat Med. 2012 Jan 29;18(2):307-14
  11. He YX, Liu Z, Pan XH, Tang T, Guo BS, Zheng LZ, Xie XH, Wang XL, Lee KM, Li G, Cao YP, Wei L, Chen Y, Yang ZJ, Hung LK, Qin L, Zhang G (Corresponding Author). Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model. Osteoporos Int. 2012 Jan;23(1):377-89.
  12. Wang X, Zhen L, Zhang G, Wong MS, Qin L, Yao X. Osteogenic effects of flavonoid aglycones from an osteoprotective fraction of Drynaria fortunei--an in vitro efficacy study. Phytomedicine. 2011 Jul 15;18(10):868-72.
  13. He YX, Zhang G (Corresponding Author), Pan XH, Liu Z, Zheng LZ, Chan CW, Lee KM, Cao YP, Li G, Wei L, Hung LK, Leung KS, Qin L(Corresponding Author). Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model. Bone. 2011 Jun 1;48(6):1388-400.
  14. Xie XH, Wang XL, Zhang G, Liu Z, Yao D, Hung LK, Hung VW, Qin L. Impaired bone healing in rabbits with steroid-induced osteonecrosis. J Bone Joint Surg Br. 2011 Apr;93(4):558-65.
  15. Tang T (Co-first author), Zhang G (Co-first author), Lau CP, Zheng LZ, Xie XH, Wang XL, Wang XH, He K, Patrick Y, Qin L, Kumta SM. Effect of water-soluble P-chitosan and S-chitosan on human primary osteoblasts and giant cell tumor of bone stromal cells. Biomed Mater. 2011 Feb;6(1):015004
  16. Song XS, Zhou XZ, Zhang G, Dong QR, Qin L. Low-dose X-ray irradiation promotes fracture healing through up-regulation of vascular endothelial growth factor. Med Hypotheses. 2010 Dec;75(6):522-4.
  17. Xie XH, Wang XL, Zhang G, He YX, Wang XH, Liu Z, He K, Peng J, Leng Y, Qin L. Structural and degradation characteristics of an innovative porous PLGA/TCP scaffold incorporated with bioactive molecular icaritin. Biomed Mater. 2010 Oct;5(5):054109.
  18. Wang XL, Wang NL, Gao H, Zhang G, Qin L, Wong MS, Yao XS. Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei. Nat Prod Res. 2010 Aug;24(13):1206-13.
  19. Zhang P, Qin L, Zhang G. The potential application of nicotinic acetylcholine receptor agonists for the treatment of rheumatoid arthritis. Inflamm Res. 2010 Jun;59(6):415-7.
  20. Qin L, Wang L, Wong MW, Wen C, Wang G, Zhang G, Chan KM, Cheung WH, Leung KS. Osteogenesis Induced by Extracorporeal Shockwave in Treatment of Delayed Osteotendinous Junction Healing. J Orthop Res. 2010 Jan;28(1):70-6.
  21. Wang HH, Wang YX, Griffith JF, Sun YL, Zhang G, Chan CW, Qin L, Ahuja AT, Teng LS. Pitfalls in interpreting rat knee joint magnetic resonance images and their histological correlation. Acta Radiol. 2009 Nov;50(9):1042-8
  22. Zhang G, Sheng H, He YX, Xie XH, Wang YX, Lee KM, Yeung KW, Li ZR, He W, Griffith JF, Leung KS, Qin L. Continuous occurrence of both insufficient neovascularization and elevated vascular permeability in rabbit proximal femur during inadequate repair of steroid-associated osteonecrotic lesions. Arthritis Rheum. 2009 Oct;60(10):2966-77.
  23. Peng S (Co-first author), Zhang G (Co-first author), He Y, Wang X, Leung P, Leung K, Qin L. Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone. Bone. 2009 Sep;45(3):534-44
  24. Zhang G, Wang XL, Sheng H, Xie XH, He YX, Yao XS, Li ZR, Lee KM, He W, Leung KS, Qin L. Constitutional flavonoids derived from Epimedium dose-dependently reduce incidence of steroid-associated osteonecrosis not via direct action by themselves on potential cellular targets. PLoS One. 2009 Jul 29;4(7):e6419.
  25. Sheng H, Zhang G, Wang YX, Yeung DK, Griffith JF, Leung KS, Qin L. Functional perfusion MRI predicts later occurrence of steroid-associated osteonecrosis: an experimental study in rabbits. J Orthop Res. 2009 Jun;27(6):742-7.
  26. Wang HH, Wang YX, Sheng H, Zhang G, Qin L, Ahuja AT, Teng LS. Fossa trochanterica of the proximal femur in rabbits: an anatomic structure for potential misinterpretation on magnetic resonance images. Acta Radiol. 2009 Mar;50(2):212-6.
  27. Zhang G, Qin L, Sheng H, Wang XL, Wang YX, Yeung DK, Griffith JF, Yao XS, Xie XH, Li ZR, Lee KM, Leung KS. A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated osteonecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner. Bone. 2009 Feb;44(2):345-56.
  28. Zhou XZ, Zhang G, Dong QR, Chan CW, Liu CF, Qin L. Low-dose X-irradiation promotes mineralization of fracture callus in a rat model. Arch Orthop Trauma Surg. 2009 Jan;129(1):125-32.
  29. Qin L, Zhang G, Sheng H, Wang XL, Wang YX, Yeung KW, Griffith JF, Li ZR, Leung KS, Yao XS. Phytoestrogenic compounds for prevention of steroid-associated osteonecrosis. J Musculoskelet Neuronal Interact. 2008 Jan-Mar;8(1):18-21.
  30. Wang XL, Wang NL, Zhang Y, Gao H, Pang WY, Wong MS, Zhang G, Qin L, Yao XS. Effects of eleven flavonoids from the osteoprotective fraction of Drynaria fortunei (KUNZE) J. SM. on osteoblastic proliferation using an osteoblast-like cell line. Chem Pharm Bull (Tokyo). 2008 Jan;56(1):46-51.
  31. Zhang G, Qin L, Shi Y. Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. J Bone Miner Res. 2007 Jul;22(7):1072-9.
  32. Zhang G, Qin L, Sheng H, Yeung KW, Yeung HY, Cheung WH, Griffith J, Chan CW, Lee KM, Leung KS. Epimedium-derived phytoestrogen exert beneficial effect on preventing steroid-associated osteonecrosis in rabbits with inhibition of both thrombosis and lipid-deposition. Bone. 2007 Mar;40(3):685-92.
  33. Hao YJ, Zhang G, Wang YS, Qin L, Hung WY, Leung K, Pei FX. Changes of microstructure and mineralized tissue in the middle and late phase of osteoporotic fracture healing in rats. Bone. 2007 Oct;41(4):631-8.
  34. Qin L, Zhang G, Sheng H, Yeung KW, Yeung HY, Chan CW, Cheung WH, Griffith J, Chiu KH, Leung KS. Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone. Bone. 2006 Oct;39(4):863-71.
  35. Zhang G, Qin L, Hung WY, Shi YY, Leung PC, Yeung HY, Leung KS. Flavonoids derived from herbal Epimedium Brevicornum Maxim prevent OVX-induced osteoporosis in rats independent of its enhancement in intestinal calcium absorption. Bone. 2006 Jun;38(6):818-25.
  36. Zhang G (Corresponding Author), Qin L, Shi Y, Leung K. A comparative study between axial compression and lateral fall configuration tested in a rat proximal femur model. Clin Biomech (Bristol, Avon). 2005 Aug;20(7):729-35.
  37. Qin L, Zhang G, Hung WY, Shi Y, Leung K, Yeung HY, Leung P. Phytoestrogen-rich herb formula "XLGB" prevents OVX-induced deterioration of musculoskeletal tissues at the hip in old rats. J Bone Miner Metab. 2005;23 Suppl:55-61.